GIPERALDOSTERONIZM

GIPERALDOSTERONIZM, sindrome, ki dar natijai dar organizm bisyor budani miqdori gormoni qishri gadudi boloi gurdaho – aldosteron rukh menamoyad. Aldosteron dar kori tanzimi mubodilai moddaho dar organizm shirkat mevarzad. On baroi dar organizm bozdoshta shudani ionhoi natriy musoidat karda, ionhoi kaliy va gidrogenro ba vositai peshob khorij menamoyad. Tarashshuhi aldosteronro sistemai renin-angiotenzin tanzim mesozad. Miqdori mutadili aldosteron dar khun 2 – 17 ng/100 ml ast; ba vositai peshob dar yak shaboruz 15 – 80 mkg aldosteroni payvast, 0,05 – 0,3 mkg aldosteroni ozod va 3 – 16 mkg aldosteroni ba kislota noustuvor khorij karda meshavad.
G. metavonad yakumin va duyumin boshad. G.-i yakumin (sindromi Konn) dar mavridi tarashshuhi ziyodi aldosteron, ki sababi on paydoishi adenoma (aldosteronoma yo aldosteroma) va saratoni qishri gadudi boloi gurdaho ast, ba vujud meoyad. G.-i duyumin dar natijai afzudani faoliyati renin hangomi bemorihoe, ki khungardishro dar gurdaho dushvor mesozand, omoshoi gurda, kam istemol kardani namak, benazorat istifoda burdani doruhoi peshobron va mushil (isholovar) paydo meshavad.
G.-i yakuminro bo usuli jarrohi tabobat mekunand. Hangomi G.-i duyumin az usulhoi tabobati aloimi istifoda karda meshavad.
Bo maqsadi peshgirii G. odamoni fishori khunashon baland, giriftori amrozi jigar va gurdaho boyad muntazam az nazorati dukhtur guzarand.