Nazariyai harorati yo garmi

Reaksiyai galizshavie, ki ba hosil gashtani polimerho ovarda merasonad, az payvastagihoi khurdmolekula bo rohi garm kardan amali meshavad. Nisbat ba digar qismathoi materiyai zinda sintezi polipeptidho beshtar omukhta shudaast.

Tashabbuskori sintezi polipeptidho bo rohi harorati olimi amerikoi S.Foks meboshad. U muddati tuloni ba omuzishi imkoniyati hosilshavii peptidho dar sharoiti avvalini Zamin saru kor dosht. Agar omekhtai aminokislotahoro dar sharoiti mutadil yo dar muhiti inerti to harorati 180 – 2000 S garm kunem, reaksiyai tajziya ba amal omada dar natija oligomerhoi nachandon kaloni monomerhoyashon bo bandi peptidi payvastbuda va miqdori kami polipeptidho hosil meshavad.

Agar ba omekhtai avvalini aminokislotaho kislotai asparagin va glutamin ilova karda shavad, miqdori polipeptidho meafzoyad. Massai molekulavii polimerhoi bo in usul hosilshuda ba yakchand hazor Dalton (D) barobar ast (Dalton vohidi chenaki massa, miqdoran ba massai yak atomi gidrogen 1,67kh10-24 g barobar meboshad).

Polimerhoe, ki bo rohi garmi az aminokislotaho girif ta meshudand, proteinoidho buda, onho bisyor khosiyathoi biopolimerhoi proteinmonandro zohir mekardand. Ammo bo usuli harorati dar mavridi galizshavi (kondensatsiya)i nukleotidho va monosakharidhoi sokhtorashon murakkab hosil gashtani kislotahoi nukleinat va polisakharidhoi hozir malum buda, az ehtimol dur ast.