ADRENALIN

ADRENALIN (Adrenalinum; az lot. ad – nazdi va renalis – gurdagi), gormoni gadudi boloi gurda. Massai mol. 183; moddai kristallii safed; az chihati optiki faol ast. Dar obi garm, kislotaho va ishqorho hal meshavad. Moddai noustuvor buda, ba hosilahoi gunogun tabdil meyobad. A. avvalin gormonest, ki dar holati kristalli chudo va sintez karda shudaast. Az aminokislotaho (fenilalanin va tira- zin) dar gurushahoi khromaffinii gadudi boloi gurda hosil meshavad. A. ba khun dokhil shuda, talaboti uzvu boftahoro ba oksigen afzun megardonad; bahri faol sokhtani glikogen, ki tachziyai on boisi dar khun baland shudani qand megardad, shirkat mevarzad; mubodilai safeda, karbogidratho, charb va g.-ro behtar menamoyad; raghoi khunro tang karda, fishori sharayonro baland mebardorad; kori dilro metezonad; kori medayu rudahoro behtar mesozad. Tasiri A. kutohmuddat ast, zero zud (asosan dar chigar) oksid meshavad. Be- run az organizm niz oksid shudanash mumkin ast. Hangomi baze bemorihoi uzvhoi darun, silsilai asab, gadudhoi usorai dokhili (endokrini) va g. miqdori A. dar organizm tagyir yofta, ravandi bemoriro dushvor menamoyad. Bo maqsadi tabobat A.- ro az gadudi boloi gurdai hayvonot megirand yo bo rohi sintez ba dast meorand. Mahluli namaki khloridi A. hangomi past shudani fishor, bemorii ziqi nafas, bemorihoi allergi, hamchunin dar vaqti behissozii chuzi va charrohi (baroi qati khunravi) ba zeri pust firistoda meshavad. A.-ro dar mavridi bemorii gipertoniya, ateroskleroz, illati dil va g. istifoda burdan mumkin nest.
Ad.: Adrenalin i noradrenalin, M., 1964; Mar- ri R., Grenner D., Biokhimiya cheloveka, ch. 1 – 2, M., 1993; Marshall V.J., Klinicheskaya biokhimiya, M., 2000. F. A. SHukurov.