MUKOVISSIDOZ

MUKOVISSIDOZ (Mucoviscidosis; lot. mucus – luob va viscidus – chaspak), kistofibrozi gadudi zeri meda, pankreofibroz, bemorii irsi, ki dar mavridi on faoliyati gadudhoi tarashshuhi beruni khalal meyobad. YAke az bemorihoi mamuli irsi buda, tanosubi on dar bayni navzodho taqr. 1 : 2000 ast.
M. purra tadqiq nashudaast. Bino ba baze malumot on enzimopatiyai irsi buda, bo rohi autosomi-retsessivi meros memonand. Alomati M. nuqsi fermenthoe meboshad, ki dar kori hosil shudani polisakharidho (dar tarkibi luobe, ki dar gadudhoi endokrinii luobpardai ruda, rohi nafas, majroi talkha va gadudi zeri meda hosil meshavand, mavjudand) ishtirok menamoyand. Dar natija khosiyathoi fiziki va khimiyavii tarashshuhot tagyir yofta, on chaspak meshavad, majroi gadudro mebandad, binobar in dar gadud digargunihoi kistozi rukh medihand, faoliyati uzvhoi marbuta (ruda, shush, jigar, gadudi zeri meda) tagyir meyobad.
M.-ro dar bemorkhona tabobat mekunand. Hangomi basta budani rudaho jarrohii ojil zarur ast; khelhoi digari bemori bo parhez, vitaminho, doruhoi fermenti, gormonhoi anaboli, guzaronidani plazma va g. muolija karda meshavad.