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MAGZI USTUHON

magzi-ustugonMAGZI USTUHON (Medulla ossium), uzvi khunu ustukhonofar va hifzi biologii organizm; dar javfi moddai isfanjii ustukhon joy giriftaast.
Tashakkuli M. u. dar tifli batn dar okhiri mohi seyumi rushdi on khotima yofta, dar mohhoi 4 – 5 ba faoliyat (hosil kardani khun) ogoz mekunad. Dar navzodon massai M. u. taqr. 40 g (1,4% massai badan) ast. Bo mururi sabzishi ustukhon va kalon gashtani hajmi javf massai M. u. afzuda, dar odami kalon ba 2600 – 3000 g (taqr. 4,6% massai badan) merasad. M. u. hamchunin dar tajziyai eritrositho, istifodai ohan, sintezi gemoglobin ishtirok namuda, zakhiragohi lipidho ast. Azbaski M. u. dar tarkibi khud limfositho va fagosithoi mononukleini dorad, dar aksulamalhoi masuni (immuni) shirkat menamoyad.
M. u. surkh va zard meshavad. M. u.-i surkh (mieloidi) boftai faoli khunofar ast; dar on hujayrahoi khun (eritrositho, granulositho, limfositho, monositho, trombositho) tashakkul meyoband. M. u.-i zard (charbi) chandon faol nabuda, az hujayrahoi charbi tarkib yoftaast. Dar boftahoi M. u. raghoi sershumori khungard va shabakai muraghoi sinusoidi mavjudand, ki tavassuti masomai onho boftai khunofari M. u. bevosita bo khun tamos dorad. Dar M. u. hujayrahoi nobolig va boligi khun duchor meoyand; on hamchunin az unsurhoe, ki mansubi fagosithoi mononukleini meboshand, gani ast.
Tanosubi M. u. – i surkh va zard gunogun buda, ba sinnu sol, tasiri omilhoi endogeni va ekzogeni vobastagi dorad. Dar davrahoi avvali kudaki dar ustukhonhoi pahn va naychashakl M. u.-i surkhi faol mavjud ast, ki badi 4 sol tadrijan bo hujayrahoi charbi ivaz meshavad. Dar sinni 25-solagi diafizi ustukhonhoi naychashakl az hujayrahoi charbi pur meshavad; dar ustukhonhoi pahn onho taqr. 50%-i javfro ishgol menamoyand. Dar pironsoli miqdori hujayrahoi charbi dar M. u. tadrijan meafzoyad.
Tahqiqi gistologii M. u. ba maqsadi arzyobii vazi khunofari, tasdiqi tashkhisi bemorihoi khun, mas., kamkhuni, leykozho, hamchunin sanjishi natijai tasiri doruho guzaronda meshavad. M. u.-ro bo usuli trepanobiopsiya megirand: bo suzani makhsus ustukhoni tihigoh yo devorai peshi ustukhoni chanog (sarsina)-ro shikofta, kame M. u.-ro berun meorand.

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