INSULIN

INSULIN (lot. insula – jazira, jaziracha), gormone, ki beta-hujayrahoi jazirachahoi gadudi zeri meda hosil mekunand. I. omili asosii nazorati mubodila va dar organizm gun shudani safedaho, ravgan va angishtobho meboshad. Vobasta ba sokhtori khimiyavi I. polipeptidi murakkab buda, tarkibi on dar hayvonoti gunogun farq mekunad. I. ba tavassuti retseptorhoi makhsus, ki dar sathi hujayrahoi boftahoi insulinkhoh joy giriftaand, tasir merasonad. Angezai asosii tarashshuhi I. dar organizm glyukoza ast. Dar mavridi dar beta-hujayrahoi jazirachahoi gadudi zeri meda kam hosil gashtani I., ba majroi khun khorij shudani I.-i nofaol yo nisbati I. sust shudani hassosiyati boftaho diabeti qandi inkishof meyobad. I. hangomi omose, ki az beta-hujayrai jazirchaho barmeoyad (insuloma) bisyor khorij meshavad.
Doruhoi I.-ro az gadudi zeri medai gov va khukho megirand. Onho baroi tabobati diabeti qandi va bemorihoi ruhi (insulinoterapiya) istifoda megardand. I. saviyai glyukozaro dar khuni bemoroni giriftori diabeti qandi tez past mekunad, vale tasiri on az 6 soat besh nest. Dar natijai ba I. ilova kardani namakhoi rukh va safedahoi gunogun tasiri on 10 – 36 soat idoma meyobad.