GORMONOTERAPIYA

GORMONOTERAPIYA (Hormonotherapia), ba tavassuti doruhoi gormoni muolija kardani bemorihoi gunogun. G.-ro dar mavridi bemorihoi endokrini va gayriendokrini istifoda mebarand. Vobasta ba vazi faoliyati gadudhoi usorai dokhili (endokrini) G. tavizi, angezishi va tasakkuni meshavad.
G.-i tavizi hangomi sust shudani faoliyati gadudi usorai dokhili bo maqsadi raf sokhtani norasoii gormonho istifoda megardad. Ba bemor doruhoi hamon gormon yo davohoi shabeh ba onhoro tain mekunand. G.-i tavizi faqat dar davrai istifodai gormonho yo doruhoi gormoni naf dorad, zero onho sababhoi bemoriro bartaraf namesozand. In navi G. tamomi umr idoma meyobad, mas., bo insulin tabobat kardani diabeti qandi; bo glyukokortikoidho yo davohoi on muolija namudani bemorii Addison; bo gormonhoi tireoidi darmon bakhshidani gipotireoz va g. Voyai doruhoi gormoni ba tavri fardi intikhob karda meshavad.
G.-i angezishi bahri faol sokhtani kori gadudi usorai dokhili amali megardad. Bo in maqsad az gormonhoi hissai peshi gipofiz va neyrogormonhoi gipotalamus istifoda mekunand. G.-i angezishii bardavom khele kam kor farmuda meshavad (asosan baroi muolijai gipogonadizmi duyumin).
G.-i tasakkuni baroi muolijai giperfunksiyai mutlaq yo nisbii gadudhoi usorai dokhili yo omoshoi vobasta ba gormon istifoda megardad. Dar asnoi on faoliyati gormoni bemoriovar qat karda meshavad yo ba organizm gormone mefiristand, ki ziddi on tasir merasonad.
Dar mavridi bemorihoi gayriendokrini G. beshtar tasiri patogenezi merasonad, zero on ba mekhanizmhoi inkishofi bemori tasir meorad. Hangomi in navi G. beshtar az gormonhoi qishri gadudhoi boloi gurda – glyukokortikoidho istifoda karda meshavad.
Dar kudakon G. zeri nazorati qatii dukhtur surat megirad (tagyiri massai badan va holati medayu rudahoro muntazam nazorat menamoyand).