GLYUKAGON

GLYUKAGON, yak nav gormon, antagonisti fiziologii insulin. G. dar tanzimi mubodilai karbogidratho ishtirok karda, ba mubodilai charbu tasir merasonad, ba faoliyati fermenthoe, ki charburo tajziya mekunand, taqviyat mebakhshad. G. peptid ast. Onro asosan alfa-hujayrahoi jazirachai gadudi zeri meda sintez mekunad. Muqarrar shudaast, ki G. az jonibi hujayrahoi makhsusi luobpardai rudai duvozdahangushta va meda niz hosil meshavad. G. ba khun hamroh shuda, miqdori glyukozaro ziyod mekunad; dar natija bemorii giperglikemiya inkishof meyobad. Dar surati mutadil budani miqdor, G. ba bisyor past shudani saviyai glyukoza roh namedihad. Binobar mavjudiyati G., ki tasiri gipoglikemiyavii insulinro bartaraf mekunad, mubodilai glyukoza dar organizm ba meyor medaroyad. G. dar jigar ravandi ba glyukoza tabdil yoftani glikogenro metezonad; on ba glikogeni tarkibi mushakho tasir namerasonad. Miqdori G. dar khun hangomi bemorii diabeti qandi ziyod meshavad. Norasoii G. boisi khuruji nogahonii gipoglikemiya (khususan dar kudakon) khohad shud. Az rui meyor miqdori G. dar khun 0,5 – 6 ng/ml ast.