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GISTAMIN

gistaminGISTAMIN, moddai az nigohi fiziologi faol; mansubi guruhi aminhoi biogeni ast. G. dar organizm az aminokislotaho – gistidin hosil meshavad; on ba miqdori ziyod dar hujayrahoi zakhim (farbeh) niz vujud dorad. G. kamubesh ba vositai gizo ham ba organizm vorid meshavad. G. dar tarkibi khun asosan dar shakli payvasti gayrifaol mavjud ast (dar plazma az 0 to 5 mkg/g gistamini ozod vujud dorad). Samarai fiziologii G. dar afzun gardondani qobiliyati nufuzpazirii devorai raghoi khurd meboshad. Binobar in G. dar on joe ki hosil shudaast, dar tanzimi mikrosirkulyatsiya shirkat mevarzad, ba rondani shirai hozima musoidat menamoyad. G. ba sifati mediator dar paydoishi aksulamalhoi allergi ishtirok mekunad, mas., hangomi sagles, varami Kvinke, bronkhospazm. Dar plazmai khun va dig. moeoti biologi barziyod gun shudani G. (mas., hangomi shoki anafilaksi; nig. Anafilaksiya) boisi ikhtiloli umumii organizm megardad.
Digidrokhloridi gistamin (Histaminum dihydrochloridum) doru buda, dar shakli khoka yo ampula istehsol meshavad. Onro ba pust mefiristand, dar shakli marham istifoda mebarand, bo rohi elektroforez kor mefarmoyand (hangomi artrit, tarbod, radikulit, pleksit va g.).

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