GENODERMATOZHO

GENODERMATOZHO (Genodermatosis; az yun. genos – paydoish va dermatozho), bemorihoi irsii pust, ki binobar mutatsiyai genho (baroi inkishof va faoliyati mutadili pust zarurand) rukh menamoyand. G. metavonand dar natijai mutatsiyai yak gen (G.-i monogeni) yo tasiri mutaqobili genho va omilhoi gunogun ba vujud oyand (G.-i gunogunomil). Illati irsii pust dar asnoi bemorihoi khromosomi, mas., sindromi Daun niz ba mushohida merasad. G.-i gunogunomil (psoriaz, neyrodermit va g.) nisbatan beshtar vomekhurand. Onho bo rohi autosomi – dominanti, goho autosomi – retsessivi ba merosi meguzarand.
G. aksaran badi tavallud yo dar mohhoi avvali hayoti kudak mushohida meshavand; baze G. (mas., sindromi Verner) dar kalonsolon padid meoyand. G. metavonand az bemorihoi uzvhoi dokhili niz darak dihand (sindromi Peyts – Egers – Turen). Bisyor G. tarzi muolijai bosamar nadorand.