GEMOGLOBINOPATIYA

GEMOGLOBINOPATIYA (Haemoglobinopathia; az gemoglabin va yun. pathos – dard, bemori), gemoglobinozho, guruhi bemorihoi irsiro guyand, ki ba ikhtiloli sokht va hosil shudani gemoglobin vobasta ast. Gemoglobin moddai rangbakhshi khun buda, dar tarkibi eritrositho mavjud ast; vay ba oksigen payvast shuda, onro ba boftahoi organizm burda merasonad. Agar gemoglobin nuqsi ziyod doshta boshad, on albatta dar zuhuroti klinikii bemori aks meyobad. G. asosan dar navohii muayyani geografi vujud dorad, mas., dar Afrika, sohilhoi Bahrhoi Miyonazamin, Osiyo Jan. SHarqi, Osiyoi Markazi, jazirahoi uqyonusi Orom va g.
G. metavonad bealomat jarayon girad; bazan bemori ba shakli kamkhuni padid meoyad. G.-ro bo usulhoi makhsus tashkhis mekunand. Az hama usuli asosi tadqiqi sokhti hujayrahoi surkhi khun (eritrositho) va gemoglobin meboshad.
Dar jumhurihoi Zakavkaziya va Osiyoi Markazi bemorii talassemiya duchor meoyad, ki navi irsii G.-i kudakon buda, hangomi on eritrositho tez taboh megardand. Talassemiya du nav – ayon va mahdud meshavad. Dar asnoi talassemiya kamkhunii shadid, varam kardani jigar va sipurz, zard gashtani pust, ikhtiloli sokhti ustukhon ruy medihad. Zimni G. inkishofi jismonii kudak sust meshavad. Muolijai in nav G. dushvor buda, onro zeri nazorati doimii dukhtur meguzaronand. Baroi tabobat az doruhoi kislotai foliat, vitamini V12 istifoda mebarand, khun meguzaronand, bazan sipurzro burida mepartoyand.
Baroi bemorone, ki giriftori navi makhsusi kamkhunii ba istiloh «hujayrai dosshakl»-and sayrugasht dar havoi kamoksigen khatarnok ast. Peshgirii G. dar mavzehoe, ki on pahn shudaast, khele muhim meboshad. Agar volidon ba navhoi vaznini bemori giriftor boshand, pas farzandi onho niz bo G.-i irsi tavallud meyobad. Az in ru, nikohi kheshovandoni nazdik joiz nest; pesh az izdivoj ba dukhturi konsultatsiyai tibbiyu genetiki murojiat kardan mufid ast.