ANTIKOAGULYANTHO (Anticoagulantia; az anti… va lot. coagulans – lakhtaband), doruhoe, ki sadi lakhtabandii khun gashta, bo in roh hosil shudani sudda (tromb)-ro peshgiri menamoyand. A. tasiri bevosita va bavosita dorand. Ba A.-i tasirashon bevosita geparin va gidrositrati natriy, ba A.-i tasirashon bavosita neodikumarin, sinkumar, fenilin, amefin mansuband.
A.-ho az rui baze khosiyatho az yakdigar farq dorand. A.-i tasirashon bevosita mustaqiman ba omilhoi lakhtabandi, ki dar khun gardish mekunand, tasir merasonand. Mas., geparin faoliyati tromboplastin, trombin va g.-ro furu menishonad; gidrositrati natriy boshad ionhoi ozodi kalsiyro, ki dar mavridi hosil shudani tromboplastin shirkat mevarzand, payvast menamoyad.
A.-i tasirashon bavosita antagonisthoi vitamini K meboshand (vitamini mazkur hangomi hosil shudani protrombin dar jigar ishtirok mekunad). Onho ba faoliyati omilhoi lakhtabandii khun tasir namerasonand.
Tabobat bo A.-ro dukhtur tain karda, onro zeri nazorat megirad. Orizai khavfnoki muolija bo A. khunravihoi gunogun ast. Dar mavridi rukh namudani nishonahoi khunravi muolijaro qat mekunand.
Инчунин кобед
LATIFAHO
TUYONA OYAD… SHakhse ba dustash uzr ovard:j – Bubakhsh, man ba tuyat rafta nametavonam. Vay …